Sebastian Brandner Selected Research

Tyrosine (L-Tyrosine)

1/2016	Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling.
6/2014	A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.
11/2007	ERK activation causes epilepsy by stimulating NMDA receptor activity.

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Sebastian Brandner Research Topics

Disease

46	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2022 - 03/2003
28	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2022 - 03/2003
27	Glioma (Gliomas) 06/2022 - 01/2013
21	Neoplasms (Cancer) 12/2021 - 03/2004
21	Infections 09/2015 - 10/2003
16	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2011
13	Glioblastoma (Glioblastoma Multiforme) 05/2022 - 03/2004
12	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2020 - 08/2010
12	Bovine Spongiform Encephalopathy (Mad Cow Disease) 01/2020 - 03/2003
12	Scrapie 11/2013 - 03/2003
9	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 05/2022 - 11/2013
7	Kuru 11/2015 - 03/2008
6	Disease Progression 01/2022 - 09/2002
5	Astrocytoma (Pilocytic Astrocytoma) 05/2022 - 10/2015
5	Dementia (Dementias) 10/2020 - 01/2014
4	Epilepsy (Aura) 10/2022 - 11/2007
4	Oligodendroglioma 01/2022 - 10/2019
4	Brain Neoplasms (Brain Tumor) 01/2021 - 01/2013
4	Sporadic Creutzfeldt-Jakob Disease 04/2016 - 03/2008
4	Acquired CJD 08/2010 - 12/2004
3	Meningioma (Meningiomas) 12/2021 - 01/2015
3	Cognitive Dysfunction 01/2020 - 09/2010
3	Overactive Urinary Bladder (Overactive Bladder) 05/2010 - 06/2009
2	Aneurysm (Aneurysms) 10/2022 - 06/2021
2	Intracranial Aneurysm (Cerebral Aneurysm) 10/2022 - 06/2021
2	Chronic Wasting Disease 01/2022 - 10/2010
2	Medulloblastoma 12/2021 - 07/2004
2	Pituitary Neoplasms (Pituitary Adenoma) 12/2020 - 12/2014
2	Carcinogenesis 12/2020 - 10/2019
2	Parkinson Disease (Parkinson's Disease) 10/2020 - 06/2013
2	Chordoma 01/2020 - 10/2017
2	Hydrocephalus (Hydrocephaly) 03/2018 - 01/2014
2	Normal Pressure Hydrocephalus 07/2017 - 01/2014
2	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2017 - 03/2011
2	Brain Injuries (Brain Injury) 06/2016 - 11/2011
2	Brain Diseases (Brain Disorder) 04/2016 - 01/2016
2	Amyloid Plaque 02/2016 - 11/2013
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2015 - 01/2014
2	Proteostasis Deficiencies 01/2013 - 08/2012
2	Gliosis 03/2012 - 10/2010
1	Nervous System Diseases (Neurological Disorders) 10/2022
1	Seizures (Absence Seizure) 01/2022
1	Lymphoma (Lymphomas) 01/2022
1	Temporal Lobe Epilepsy 01/2022
1	Pathologic Processes 01/2022
1	Pleomorphic Adenoma 11/2021
1	Thrombosis (Thrombus) 06/2021

Drug/Important Bio-Agent (IBA)

50	PrionsIBA 01/2022 - 03/2003
36	Prion ProteinsIBA 01/2022 - 03/2003
22	Biomarkers (Surrogate Marker)IBA 06/2022 - 10/2010
19	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2003
14	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2011
9	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 05/2022 - 10/2019
6	Pharmaceutical PreparationsIBA 01/2022 - 01/2016
6	Codon (Codons)IBA 01/2022 - 11/2008
6	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2004
6	RNA (Ribonucleic Acid)IBA 11/2021 - 09/2013
5	Temozolomide (Temodar)FDA LinkGeneric 05/2022 - 03/2004
5	Histones (Histone)IBA 04/2021 - 11/2017
4	Valine (L-Valine)FDA Link 12/2020 - 10/2010
4	Growth Hormone (Somatotropin)IBA 12/2018 - 09/2015
4	Methionine (L-Methionine)FDA Link 01/2016 - 07/2006
3	EnzymesIBA 01/2022 - 07/2009
3	Monoclonal AntibodiesIBA 01/2022 - 03/2003
3	ChromatinIBA 12/2021 - 01/2013
3	tau Proteins (tau Protein)IBA 10/2020 - 04/2012
3	Tyrosine (L-Tyrosine)FDA Link 01/2016 - 11/2007
3	Peptide Hydrolases (Proteases)FDA Link 05/2015 - 06/2006
3	beta CateninIBA 07/2009 - 11/2003
3	Protein Isoforms (Isoforms)IBA 02/2007 - 03/2003
2	Glutamic Acid (Glutamate)FDA Link 10/2022 - 01/2017
2	AminesIBA 06/2022 - 01/2022
2	AmidesIBA 06/2022 - 01/2022
2	MicroRNAs (MicroRNA)IBA 01/2022 - 10/2019
2	MethyltransferasesIBA 12/2021 - 01/2021
2	Complement System Proteins (Complement)IBA 04/2021 - 01/2011
2	GadoliniumIBA 01/2021 - 04/2019
2	Peptides (Polypeptides)IBA 01/2018 - 01/2014
2	Transcription Factors (Transcription Factor)IBA 10/2017 - 12/2011
2	UbiquitinIBA 03/2016 - 03/2012
2	Proteasome Endopeptidase Complex (Proteasome)IBA 03/2016 - 11/2005
2	Apolipoproteins E (ApoE)IBA 09/2015 - 01/2014
2	Formaldehyde (Formol)FDA Link 11/2010 - 10/2010
2	Type A Botulinum Toxins (Botox)FDA Link 05/2010 - 06/2009
2	Biological ProductsIBA 11/2008 - 07/2004
1	Neurotransmitter Agents (Neurotransmitter)IBA 10/2022
1	Amyloid beta-PeptidesIBA 05/2022
1	GlucocorticoidsIBA 01/2022
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2022
1	Inositol (Myoinositol)IBA 12/2021
1	Tirofiban (Aggrastat)FDA Link 06/2021

Therapy/Procedure

12	Therapeutics 01/2022 - 03/2003
6	Radiotherapy 12/2021 - 03/2004
2	Stents 10/2022 - 06/2021
2	Drug Therapy (Chemotherapy) 12/2021 - 03/2004
2	Operative Surgical Procedures 12/2018 - 03/2005
2	Ventriculoperitoneal Shunt 07/2017 - 01/2014
1	Ligation 01/2022